Background and Objectives:
The new drug discovery process is a complex, risky, expensive, multidisciplinary activity, which requires a strong and dedicated team of medicinal / organic chemists, biologists, biochemists, pharmacologists, toxicologists, ADME scientists, analytical chemists, pharmacists and clinicians to design, discover and develop new drug candidates. Recent trend setting developments in genomics, molecular biology and pharmacology have given access to a cornucopia of new targets for drug design in therapeutic areas giving rise to both great therapeutic opportunities and greater challenges in identifying good ligands to be optimized to develop drug like candidates. Fundamental changes in the drug discovery scenario along with the continued financial pressure have opened up new opportunities and challenges for the drug industry that it has to still fully grasp. The speed of human genetics, rapid progress of bioinformatics / biotechnology and early emergence of patient focused R & D have influenced the execution of drug discovery.
The rate - limiting steps in new drug discovery are:
Besides, in spite of the access to the new armamentarium such as combinatorial chemistry, high throughput screening, computer aided drug design, rational drug design etc, there is feeling among the researchers that a major bottle neck exists downstream in drug discovery in the pharmacokinetic lead optimization, extending it to even as ADMET by resolving toxicological properties also. In such a scenario, the present workshop on "Challenges in the development of novel therapeutics" aims to focus deliberations on some of the above aspects in some important therapeutic areas besides highlighting some developments in CADD, structure and lead based drug design, molecular modeling and receptor research. With many of the Indian pharmaceutical companies entering new drug research in a big way, the workshop can help scientists to enhance their knowledge base, fine tune their thinking to stimulate creativity. Also focus their awareness on some new science which can help them translate their experience into a very productive scientific output in their own work, and convert various information on new discoveries to desirable cures.
Topics to be Covered :
The following experts have agreed to initiate deliberations on the topics outlined in the programme.
For further information contact:
Mrs. S. V. Kurup
Coordinator, Continuing Education Programme
Shri B. V. Patel Education Trust
Thaltej-Gandhinagar Highway, Thaltej,
Ahmedabad 380 054.
Tel: 079- 743 9375; 741 6409;
Fax: 079-745 0449,
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We offer computational chemistry, clinical, biology software, screening compounds, collaborative R&D & informatics services; and education aimed at NCE research.
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