Tripos Introduces Complete Laboratory Workflow
and Knowledge Management Solutions
Created for Customers, These Systems Were Quickly
Adopted in Tripos' Own
Research Laboratories
ST. LOUIS - Aug. 11, 2003 -Tripos, Inc.
(Nasdaq: TRPS), a leading provider of drug
discovery informatics products and chemistry
research, today announced the release of
ChemCoreRIO™, ChemCoreREG™ and the
Tripos Electronic Notebook™, the key
components in its new informatics solution
designed to streamline laboratory
workflows, and SARNavigator™ and
LITHIUM™, the data analysis and decision
support components in its knowledge management
solution.
"Our new laboratory workflow and knowledge
management offerings really are
tried-and-tested solutions," said Dr. John P.
McAlister, president and chief executive
officer of Tripos. "Developed initially in
response to customers' requests, these
systems proved so effective that we implemented
many of them ourselves at our
Tripos Receptor Research facility in Bude,
England. Now customers who employ our
lead screening and optimization services benefit
from the improved workflow and
knowledge-sharing that these products provide."
Tripos' new laboratory workflow system,
comprising ChemCoreRIO, ChemCoreREG
and the Tripos Electronic Notebook, is built on
Oracle, the industry-standard data
management system. Key to its success, however,
is the AUSPYX™ data cartridge which
enables Oracle to process chemical structures
just like any other pieces of data.
As its name suggests, ChemCoreRIO is a
registration, inventory and ordering system
for chemical and biological data. It's a very
flexible system that allows scientists to
enter single compounds or entire libraries using
the ChemCoreRIO forms-based user
interface or the Tripos Electronic Notebook
interface. This module helps companies
order and track reagents and also manage samples
as they move through the discovery
workflow. It can locate and order reagents,
create purchase orders, and record sample
registration and disposal; it can also integrate
with bar-code systems.
ChemCoreREG is an entry-level registration system
that can track single reagents or
entire collections. It can assign reagent
identification numbers, calculate properties
(e.g., molecular weights), handle multiple
batches, manage multiple names for single
structures, and perform queries and searching
functions.
The Tripos Electronic Notebook can be used to
streamline tasks as well as record
results. It can also support a customer's process
of becoming 21 CFR Part
11-compliant. Notebook data can be quickly
stored, searched and reused; tasks can be
initiated with a single mouse click; routine
calculations (such as yields and molecular
weights) can be automated; and a hard copy of all
the data can be generated at the end
of the experiment if necessary. Scientists can
enter experimental details such as the
reaction, apparatus, methods and results in a
standard template or customize a page to
include details about biological assay
development and screening. Experimental data
can be retrieved by searching for any combination
of data types, including starting
materials, products, reactions, researcher name,
experiment title, project, date and
yield.
LITHIUM and SARNavigator, Tripos' data-analysis
and decision-support tools, help
drug discovery team members to visualize data in
new ways. LITHIUM allows them
to display 3-D molecular models easily on their
desktop computers, thus facilitating
knowledge-sharing and discussion within the
group. LITHIUM is fully integrated with
the Windows environment and uses its familiar
user interface.
Conversely, SARNavigator is a stand-alone
spreadsheet application that allows team
members to view complex structure-activity
relationship (SAR) landscapes in 2-D. A
SAR analysis compares a molecule's structure with
its ability to affect a biological
system. SARNavigator routinely handles more than
100,000 compound datasets. And,
most important, it allows researchers to identify
and prioritize chemical series for
secondary screening, based on primary
high-throughput screening data.
About Tripos, Inc.
Tripos (Nasdaq: TRPS) combines leading-edge
technology and innovative science to
deliver consistently superior chemistry-research
products and services for the
biotechnology, pharmaceutical and other life
science industries. Tripos partners with
clients to accelerate and improve the creation of
life-enhancing products. Within
Tripos' Discovery Informatics (DI) business, the
company provides software products
and consulting services to develop, manage,
analyze and share critical drug discovery
information. Within Tripos' Discovery Research
(DR) business, Tripos' medicinal
chemists and research scientists partner directly
with clients in their research
initiatives, leveraging state-of-the-art
information technologies and research facilities.
Headquartered in St. Louis, Mo., Tripos spans the
world with global research
operations and an international client base.
Further information on Tripos can be
found at http://www.tripos.com/.
Seascape offers cutting-edge NCE Research
technologies to help bring about a quantum leap in discovery
efforts.
We offer computational chemistry, biology
software, screening compounds, collaborative R&D &
informatics services; and education aimed at NCE research.
Seascape has been a sole, authorized
representative of Tripos in India over the last eight years
and developed collaborative relationships with pharma,
biotech, acadamic and govt. labs.
Seascape operates from its offices in New Delhi
and San Francisco Bay Area. Contact us at
info@seascapelearning.com
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© 2003 Seascape
Learning, LLC
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